Good suggestions. I have been using Arturia Pigments 2 mostly, but I have tried it in multiple other synths (wavetable).
Gacki, I think the question "Is this something where the bass is up front and should be easily recognizable" is definitely applicable, because the bass line is the main element, it drives the song. I would say the arrangement I am going for is sparse, with the bass element being up front and heard.
Ozinga, I will try the doubling technique, that sounds interesting. Pigments also has a harmonics engine, I might give that a try. I did put some saturation on it, but it didn't seem to help. I am not sure my saturation plugin is that great though, and I am actively seeking some other options for saturation, I just haven't found any that l like yet.
Fisherking, when you say "lower midrange", do you have a specific frequency range you have in mind?